A.G.E. Interrupter Advanced

Sale price$290.00

The richest expression of SkinCeuticals' anti-glycation research: Pro-Xylane second on the ingredient list in a shea-based cream for very dry, deeply lined mature skin.

Key actives Niacinamide·Panthenol
When to use Morning and evening, final step, after serums
How it works

The strongest dose of the argument

Glycation, the sugar-bonding that stiffens skin's collagen and elastin with age, is this line's target, and here Pro-Xylane sits second on the ingredient list, its highest placement in the range. Niacinamide, adenosine and the blueberry-pomegranate flavonoid pair support the case.

The shea difference

Where the Ultra runs light and velvety, Advanced is built on shea butter, candelilla wax and a bench of skin-identical fatty acids: a genuinely rich cream for skin that has grown very dry, thin and deeply lined.

The calm additions

Glycyrrhetinic acid from liquorice and 4-t-butylcyclohexanol, a modern soothing agent, keep the richness comfortable on skin that flushes or prickles easily.

Who it suits

Very dry, mature skin with deep-set lines and a fragile, papery feel; skin that finds most night creams too thin by winter; and devotees of the original A.G.E. Interrupter wanting its fullest formulation.

Worth knowing

Perfumed, with limonene, coumarin and linalool on the label, so fragrance-reactive skin should sample before committing. Choosing between the two: this for very dry skin and maximum richness, A.G.E. Interrupter Ultra for a lighter feel or under makeup.

How to use

Morning and evening as the final step: warm a small amount and press over face, neck and jawline after serums.

In cold months it earns its keep as the night cream; by day, allow a few minutes before SPF.

Layering

Use alongside

Closes the routine over C E Ferulic by day or a retinal by night, and pairs with P-Tiox where expression lines join the deep ones. SPF finishes every morning.

Before you start

Not suitable if

  • Fragrance sensitivity — perfumed, with limonene, coumarin and linalool on the label

Good to know

  • Patch test on a small area of skin before first full use
Full ingredients

Aqua/Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii (Shea) Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera (Candelilla Wax), Behenyl Alcohol, PEG-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-t-Butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Parfum/Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate

Verified against Australian stock on 14 September 2026.