Medik8 Retinol & Retinal

Medik8 built its reputation on vitamin A, and this page is the whole of it: the Crystal Retinal ladder from 1 to 20, the Intelligent Retinol 3TR, 6TR and 10TR serums, the original Retinol 3TR, both eye retinoids, the overnight Night Ritual Vitamin A, and Bakuchiol Peptides for the nights and months a retinoid is off the table. Retinoids are the one ingredient class with decades of evidence for lines, texture, pigmentation and breakouts, and the difference between Medik8's options is mostly about speed and comfort. Below is how we tell them apart in clinic, and which one suits a first-timer, a returner and a veteran.

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17 products

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Medik8 Crystal Retinal 3 30ml vitamin A night serum with product box
Medik8
Crystal Retinal 3
Sale price$79.20 Regular price$99.00

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medik8 crystal retinal 10 stable retinal night serum 30ml
Medik8
Crystal Retinal 10
Sale price$140.80 Regular price$176.00

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Medik8 Crystal Retinal Ceramide Eye 6 smooth and lift eye cream 15ml
Medik8
Crystal Retinal Ceramide Eye 6
Sale price$87.20 Regular price$109.00

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Medik8 Crystal Retinal 1 gentle retinal night serum 30ml with box
Medik8
Crystal Retinal 1
Sale price$71.20 Regular price$89.00

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Medik8 Crystal Retinal Ceramide Eye 3 smooth and lift eye cream 15ml
Medik8
Crystal Retinal Ceramide Eye 3
Sale price$68.00 Regular price$85.00

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Medik8 Night Ritual Vitamin A Age-Defying Retinol Cream shown with its white outer box and a frosted glass jar with a white lid on a plain white background.
Medik8
Night Ritual Vitamin A
Sale price$92.00 Regular price$115.00
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Medik8 Crystal Retinal 3 and Advanced Pro-Collagen + Peptide Cream duo
Medik8
Crystal Retinal 3 + Advanced Pro-Collagen Peptide Cream Duo
Sale price$202.02 Regular price$259.00

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Medik8 Bakuchiol Peptides Retinol Alternative Serum shown with its white outer box and a clear glass dropper bottle containing purple liquid, on a plain white background.
Medik8
Bakuchiol Peptides
Sale price$88.00 Regular price$110.00
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Medik8 Intelligent Retinol Eye TR serum bottle on a white background
Medik8
Intelligent Retinol Eye TR
Sale price$42.40 Regular price$53.00
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Medik8 Retinol 3TR serum bottle on a white background
Medik8
Retinol 3TR
Sale price$63.20 Regular price$79.00
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Medik8 Intelligent Retinol 3TR serum bottle on a white background
Medik8
Intelligent Retinol 3TR
Sale price$71.20 Regular price$89.00
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Medik8 Intelligent Retinol 6TR serum bottle on a white background
Medik8
Intelligent Retinol 6TR
Sale price$81.60 Regular price$102.00
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Medik8 Intelligent Retinol 10TR serum bottle on a white background
Medik8
Intelligent Retinol 10TR
Sale price$95.20 Regular price$119.00
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Medik8 Skin Renewal Travel Edit gift set of travel-size renewal essentials
Medik8 The ABC Kit anti-ageing starter set with C-Tetra 30ml, Gentle Cleanse 40ml, Retinol 3TR 15ml and Hydr8 B5 30ml in a white travel bag
Medik8
The ABC Kit
Sale price$238.00
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medik8 crystal retinal 20 stable retinal night serum 30ml
Medik8
Crystal Retinal 20
Sale price$156.00 Regular price$195.00

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Medik8 Crystal Retinal 6 super-strength night serum 30ml with product box
Medik8
Crystal Retinal 6
Sale price$108.00 Regular price$135.00

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Retinal or retinol: which Medik8 vitamin A is right for you

Both end up as retinoic acid in the skin. Retinol converts twice to get there; retinaldehyde, retinal, converts once, which makes it faster-acting and more potent at the same percentage. Medik8's Crystal Retinal is encapsulated retinal in five strengths; Intelligent Retinol is time-released retinol in three. If results in weeks matter and your skin is healthy, start with Crystal Retinal 3. If you want the gentlest possible entry, or have a known fragrance allergy, Intelligent Retinol 3TR is fragrance-free and slower by design. The full strength-by-strength guide is on our Medik8 Crystal Retinal page and in the Crystal Retinal ladder guide.

The Medik8 vitamin A range, by job

How to introduce a Medik8 retinoid

Evenings only, pea-sized, on dry skin, two to three nights a week for a fortnight, then nightly. Follow with a moisturiser; Advanced Pro-Collagen + Peptide Cream or Total Moisture both cushion the adjustment. Keep leave-on acids such as Press & Glow to the other nights, use your vitamin C in the morning, and wear SPF every day. Dryness or flaking in week two or three is the formula working, not failing; drop back a night rather than stopping.

Medik8 retinoid questions

Can I use Medik8 retinol or retinal while pregnant?

No. All retinoids are off the table during pregnancy and breastfeeding. Bakuchiol Peptides is the swap Medik8 designed for exactly that period.

Which is stronger, Intelligent Retinol 10TR or Crystal Retinal 6?

Crystal Retinal 6, comfortably. As a rule of thumb, each Crystal Retinal rung does the work of a retinol several times its percentage, which is why we move retinol users to Crystal Retinal 6 rather than 10 when they switch.

Should I use a retinoid every night?

Eventually, yes. Nightly, consistent use over months is what produces the results in the studies. Build up to it, and keep it there.

Is Epios Skin an authorised Medik8 stockist?

Yes. Every Medik8 product we sell comes through the authorised Australian supply chain, so it is genuine, in date and stored correctly. Epios Skin is run by a doctor-led skin clinic in Sydney, and Medik8 is the range our clinical team reaches for most.

Brand quick facts

Founded

2009

Origin

London, United Kingdom

Key technology

CSA Philosophy · Crystal Retinal

The approach

Medik8's CSA Philosophy is the clearest organising idea in skincare: vitamin C and sunscreen by day, vitamin A by night. Three ingredients, two steps, applied consistently.

The reasoning is that these three have more independent clinical evidence behind them than anything else available without prescription, and that most routines fail from complexity rather than from missing ingredients.

The brand's other distinguishing choice is retinaldehyde, usually shortened to retinal. Where most over-the-counter products use retinol, which converts to retinoic acid in two enzymatic steps, retinal sits one step closer. That means it acts faster at equivalent concentration. Medik8 pioneered its use in mainstream skincare and their Crystal Retinal range is built on it.

Formulations are developed and manufactured in-house at their innovation centre outside London. The brand is B Corp certified.

What to know

Medik8 is widely available. Unlike some of the ranges we carry, Medik8 sells directly in Australia and through a number of retailers. We stock it because it fits alongside what else we hold, not because it is hard to find.

Retinal is not retinol. They are different molecules at different points in the same conversion pathway. Retinal is closer to the active form, which generally means faster results and, at equivalent strength, a similar or slightly greater adjustment period. Comparing a retinal percentage to a retinol percentage is not like for like.

The range is deliberately simple. Fewer products, clearer roles. If you find multi-step routines difficult to sustain, that structure is the point rather than a limitation.

L'Oréal acquired a majority stake in 2025. The founder remains involved and formulation continues in-house, but the brand is no longer independently owned. Worth knowing if that matters to you.